ABSTRACT
Since the start of the decade, the coronavirus disease 2019 [COVID-19] pandemic has disrupted the world's healthcare system. Scientists have been engaged to bring about a therapeutic agent to help combat the dreaded disease. Many researchers have shown antivirals such as Remde-sivir and Favipiravir to be effective in the treatment;however, these drugs have a short half-life. Hence, the need for a drug delivery system that could prolong or alter their effect by increasing the potency of antivirals or vaccines has been proposed. Nanotechnology has always been at the fore-front of developing and diagnosing diseases. The idea of which can be borrowed to treat the novel coronavirus. The applicability needs to be vast as the disease has spread, and a fast, reliable, effective therapeutic and diagnostic procedure is the need of the hour. Emphasis on nanotechnology us-age through the intranasal and pulmonary route has been given and various applications have also been discussed in this review.Copyright © 2021 Bentham Science Publishers.